Tizanidine reviews

Tizanidine reviews. Jun 1, 2021 · When you first start taking tizanidine, your doctor will give you a small dose. I had an accident in 2010 and had my entire left side vertebrae fx from C3 to L5. Some side effects may occur that usually do not need medical attention. Effectiveness. Apr 26, 2023 · The FDA has not approved tizanidine to treat neck or back pain. The med works wonders on my back. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. [3] Effectiveness appears similar to baclofen or diazepam. Chlorzoxazone has an average rating of 6. sweating. severe sleepiness. 4. Management of tizanidine and clonidine withdrawal syndrome includes 3, 8 the following. 7 methods were reported for the tizanidine preparation starting from the first one that was achieved by Neumann. I take 600mg of Gabapentin 3 times a day, 6 am, 12 pm, and 6 pm. 576 mg equivalent to 4 mg tizanidine base), and the inactive ingredients, colloidal silicon dioxide, stearic acid, microcrystalline cellulose and anhydrous lactose. 58 mg equivalent to 4 mg tizanidine base, and 6. Common initial manifestations are scanning dysarthria with a characteristic drawn-out slowness of speech and gait instability. CNS depression—slow or shallow breathing, shortness of breath, feeling faint, dizziness, confusion, trouble staying awake. 1) 7. Aug 18, 2022 · Tizanidine is a drug used to treat the tendency of muscles to spasm, typically resulting from neurological problems. According to product labeling, tizanidine use requires caution in patients with renal impairment (creatinine clearance < 25 mL/min). Gabapentin is also used as an adjunct to more potent anticonvulsants and for the management of certain types of Tizanidine for Muscle Spasm User Reviews (Page 3) Brand names: Zanaflex. 4/18/2016. eu, and WHO ICTRP from inception to 23 February 2021. Improvement in muscle tone occurred in 60 to 82% of tizanidine recipients, compared with 60 to 65% of baclofen and 60 to 83% of diazepam recipients. SETTING Generic Name Tizanidine DrugBank Accession Number DB00697 Background. 115 Reviews Jun 1, 2021 · When you first start taking tizanidine, your doctor will give you a small dose. However, it is detectable in a urine test which is focused on the levels of Tizanidine specifically. 8 out of 10 from a total of 61 ratings on Drugs. And a May 2018 Cochrane review found that there’s no good evidence to support the Tizanidine is an α2 and imidazole receptor agonist at a spinal and supraspinal level resulting in reduced central sympathetic outflow and causing hypotension rarely, especially in those receiving beta-blockers or angiotensin-converting enzyme inhibitors. The mechanism by which tizanidine causes skeletal muscle relaxation is not well known; it appears to act at the level of spinal cord pain reflexes, most likely through activity as a Mar 26, 2024 · Tizanidine Dosage and Administration. (1) Hemodynamic control with adrenergic blocker drugs. Zanaflex’s half-life is roughly 2. 60% of reviewers reported a positive effect, while 26% reported a negative effect. 0 out of 10 from a total of 300 reviews for the treatment of Muscle Spasm. 5 hours 5–7. The typical starting tizanidine dosage is 2 mg every 6 to 8 hours. " It's the same with me as far as feeling mentally slow and sometimes slurring my words. Certain medications are safer and more effective than others for treating spine pain in older adults, according to a recent study. 2, comments, side effects, dosage, sex, age, time taken. Overall rating 3. Jan 25, 2024 · No, Tizanidine does not show up on a standard drug test. Wide interpatient variability in the effective plasma concentrations of tizanidine means that the optimal dosage must be titrated over 2 to 4 weeks for each patient (dosages of 2 to 36 mg/day have been used in clinical trials). Knight Pharm. Alfentanil. Your dose will then be increased at 3- to 4-day intervals until you are on a dose that suits your condition. Although skeletal muscle relaxants are recommended for short-term use in the treatment of Feb 17, 2020 · Titration and maintenance dose: Children ≥2 years and Adolescents: Oral: Titrate initial dose upward to reported effective range of: 0. In such patients, decrease the dose. Includes 5 patient ratings with average score of 3. Medications that increase tizanidine levels. Satisfaction. 48% of reviewers reported a May 31, 2019 · Introduction. It works by helping to relax the muscles. 2. 1/24/2024. Feeling sleepy. But either medication may not make much difference in new low back pain when compared with ibuprofen alone. Orphenadrine has an average rating of 6. Conclusions This review scoped all of the reported methods used for the preparation of tizanidine base starting from 4-amino-5-chloro-2,1,3-benzothiadiazole (1). Among these are the over-the-counter drugs acetaminophen (Tylenol) and ibuprofen (Advil) and some nerve pain drugs, muscle relaxants, and antidepressants. Background: Tizanidine is a centrally acting muscle relaxant with a novel mechanism of action and structurally related to clonidine. I haven't started taking it yet. These are not all of the side effects that may occur. 1. Aims: Tizanidine, one of the few oral antispastic therapies approved for use in the USA, has a narrow therapeutic index that can often make optimal patient dosing difficult. Alprazolam. 3 to 0. There are no large case series of tizanidine exposure. 12. Reviews (348) Uses . Dec 2, 2022 · Tizanidine Dosage. The maximum recommended single dose is 16 mg. Case presentation: We report a 56-year-old hypertensive male presenting with altered Tizanidine, 5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-ben-zothiadiazol-4-amine (Figure 1) is an imidazoline central alpha(2)-adre-noceptor agonist drug used to relieve spasms and treat Clinical studies have shown that modified release tizanidine improved spasticity and disability in approximately 94% and 79%, respectively, of spastic patients, and adverse effects were observed in about 33% of patients. 4mg 3X day. . Your doctor may adjust your dose as needed. It may also be called a centrally-acting muscle relaxant. 6 Specifically, central nervous system (CNS) adverse Sep 6, 2014 · Guanabenz, guanfacine, clonidine, tizanidine, medetomidine, and dexmedetomidine are all α-2 agonists that vary in their potency and affinities for the various α-2 receptor subtypes. Tizanidine does not cure these problems, but it may allow other treatment, such as physical therapy, to be more helpful in improving Jan 6, 2021 · Tizanidine (Zanaflex) received an overall rating of 6 out of 10 stars from 170 reviews. Maximum Jan 30, 2017 · Tizanidine (tye zan' i deen) is an imidazoline derivative and is a centrally acting muscle relaxant used for therapy of acute muscle spasms and chronic spasticity. Amantadine. Dosage can be increased by 2 mg to 4 mg per dose, with 1 to 4 days between increases; total daily dose should not exceed 36 mg (2. Bioavailability is 40% to 95% of the administered dose due to its extensive hepatic metabolism by CYP1A2. Ordinarily avoid concomitant use; if concomitant use is necessary, use with Feb 1, 2015 · Tizanidine Capsules and Tizanidine tablets are bioequivalent to each other under fasted conditions, but not under fed conditions. 7. Tizanidine is a fast-acting drug used for the management of muscle spasm, which may result from the effects of multiple sclerosis, stroke, an acquired brain injury, or a spinal cord injury 9. A systematic review indicated that skeletal muscle relaxants were effective in the short-term relief of acute low back pain when compared with placebo. The pharmacokinetic and clinical properties of a modified release formulation of the alpha 2-adrenergic agonist tizanidine are reviewed. Prescribed 4m tablet to take in the evening for sore joints -lower back, hips, shoulders to help me sleep. Condition: Muscle Spasm. Ease of Use. Data sources Medline, Embase, CINAHL, CENTRAL, ClinicalTrials. Liver injury—right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, unusual weakness or fatigue. Tizanidine for Muscle Spasm User Reviews (Page 3) Brand names: Zanaflex. Never take more than 36 mg of this medication in a single 24-hour period. Depending on how you respond to the medication, your prescriber may increase your doses by 2 mg to 4 mg every few days. com. Apr 11, 2017 · Health data from 2003 to 2004 revealed that cyclobenzaprine (Amrix, Fexmid, others), carisoprodol (Soma, others), and metaxalone (Metaxall, Skelaxin, others) accounted for more than 45% of medications prescribed for acute musculoskeletal pain. DESIGN . A single dose of either two 4 mg tablets or two 4 mg capsules was administered under fed and fasting conditions in an open label, four period, randomized crossover study in 96 human volunteers, of whom 81 were Jan 30, 2017 · Tizanidine (tye zan' i deen) is an imidazoline derivative and is a centrally acting muscle relaxant used for therapy of acute muscle spasms and chronic spasticity. A systematic review of tizanidine would be beneficial in consolidat - ing available data on its effects and safety for pediatric patients with CP. Feb 13, 2018 · Tizanidine shows linear pharmacokinetics with a half-life (t ½) of 2. 1 out of 10 from a total of 354 reviews on Drugs. Tizanidine belongs to the class of medicines known as central alpha-2-adrenergic agonists. Most people start off by taking 2mg of tizanidine every 6 to 8 hours, with a maximum of 3 doses per day. Oct 1, 2022 · Back Pain Healthy Aging Medications. The review reiterates the role of physical treatment in the management Tizanidine Tablets USP, 2 mg are white to off white, oval, flat, beveled edged tablets debossed with “R179” on one side and “bisecting score” on other side. These side effects may go away during treatment as your body adjusts to the medicine. . sleepiness or unusual drowsiness. 26 Its half-life is short, so frequent dosing (usually every 6–8 Aug 1, 2004 · Although this systematic review found some evidence of increased effectiveness of tizanidine compared to baclofen and diazepam, it is not possible to determine whether these conclusions are valid. Dosage and Administration. Common side effects of tizanidine include low blood pressure, dry mouth, dizziness, sleepiness, weakness, fatigue, blurred vision, and constipation. 48% of reviewers reported a positive effect, while 30% reported a negative effect. Condition: Other. It is not a substance of abuse and is not included in the list of controlled drugs. Tizanidine does not cure these problems, but it may allow other treatment, such as physical therapy, to be more helpful in improving Jun 7, 2019 · Tizanidine (Zanaflex) received an overall rating of 6 out of 10 stars from 170 reviews. Tizanidine can make you feel sleepy or dizzy. Ther­ apy with conventional tizanidine Viloxazine. After multiple spinal surgeries and 48 screws and 4 rods (full spine and neck) my muscles separated and healed deformed. 46% of reviewers reported a positive experience, while 30% reported a negative experience. Consult your doctor if pregnant or breastfeeding. 98). Read comments and ratings from patients who used tizanidine oral for muscle spasms, pain, and sleep. The central alpha 2 adrenoceptor agonist tizanidine is a myotonolytic agent used in the treatment of Oct 31, 2022 · Corresponding Author. Ticlopidine. [4] Aug 15, 2023 · Potential decreased plasma clearance of tizanidine (by ≤50%) Avoid concurrent use, if possible. , It did help me sleep during the night. Two muscle relaxants called Zanaflex and Flexeril are among the drugs Flexeril‚ or cyclobenzaprine‚ is primarily used to relieve muscle pain‚ stiffness‚ and discomfort caused by musculoskeletal conditions. I didn’t realize how bad it was until it was gone. Tizanidine is used to help relax certain muscles in your body. Clonidine, tizanidine, and dexmedetomidine have received the greatest clinical use and will be addressed more thoroughly. 288 mg equivalent to 2 mg tizanidine base and 4. How to Find 346 user ratings and reviews for Tizanidine Oral on WebMD including side effects and drug interactions, medication effectiveness, ease of use and satisfaction Find patient medical information for Tizanidine HCL on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Apr 4, 2023 · Tizanidine relaxes muscles by dampening down nerve impulses that are sent from spasming muscles along nerve fibers to the brain. Mar 1, 2014 · Freddles279 28 Feb 2018. See the pros and cons, effectiveness, ease of use, and satisfaction of this medication. The morphine and Lyrica did nothing for the back spasms. You may report side effects to the FDA at 1-800-332-1088. If you have more questions about how to take this medication, talk to your pharmacist or doctor. See what others have said about Tizanidine (Zanaflex), including the effectiveness, ease of use and side effects. Aug 15, 2023 · dizziness, faintness or lightheadedness when getting up from a lying position. 1) 6. Moreover, a systematic review can mitigate small sample sizes, Nov 12, 2015 · Tizanidine is a centrally acting α 2-agonist with muscle relaxant properties. That’s how tight muscles were for Tizanidine is used to help relax certain muscles in your body. Possible increased plasma tizanidine concentrations. Tizanidine has an average rating of 6. Methods: Retrospective review of all ingestions involving tizanidine reported to a poison control center from January 2000 through February 2003. May 1, 2024 · loss of consciousness. 54. Find 346 user ratings and reviews for Tizanidine Oral on WebMD including side effects and drug interactions, medication effectiveness, ease of use and satisfaction Clinical studies have shown that modified release tizanidine improved spasticity and disability in approximately 94% and 79%, respectively, of spastic patients, and adverse effects were observed in about 33% of patients. Tizanidine is not a first choice for new neck or back muscle pain. Benzhydrocodone. 7 out of 10 from a total of 82 ratings on Drugs. I also take 8mg of Tizanidine 3 times a day, at 6 am, 12 pm and at bedtime. I'm finishing off the rest of my Soma first. Below, we’ll cover five of the most important tizanidine interactions you should know. Dizziness. Tizanidine Tablets USP, 4 mg are white to off white, oval, flat, beveled edged tablets debossed with “R180” on one side and “quadrisecting score” on other side. A randomised double-blind study. Find 346 user ratings and reviews for Tizanidine Oral on WebMD including side effects and drug interactions, medication effectiveness, ease of use and satisfaction Overall rating 5. pale or blue lips, fingernails, or skin. Tizanidine metabolites have a t ½ of 20 to 40 hours and Gabapentin is an anticonvulsive medication that is primarily used to treat seizures and nerve pain. 5. Tizanidine hydrochloride is contraindicated in patients taking potent inhibitors of CYP1A2, such as fluvoxamine or ciprofloxacin [see - Drug Interactions (7. Nov 21, 2022 · Some tizanidine interactions should be avoided entirely. Treatment can be repeated at 6 to 8 h intervals as needed. Hallucinations. It is important for clinicians to have clear objectives in patient treatment and the available treatment strategies. A pain specialist treating me for back spasms, chronic pain, fibromyalgia put me on Tizanidine to help with the spasms. It relieves spasms, cramping, and tightness of the muscles caused by medical problems, such as multiple sclerosis or certain injuries to the spine. They differ by the dosage prescribed and treatment length, and they also have different half-lives, the time it takes for the drug to reduce by one-half, or 50 percent, in the bloodstream. Tizanidine Tablets, USP 4 4 CONTRAINDICATIONS. irregular, fast or slow, or shallow breathing. 87 mg equivalent to 6 mg tizanidine base), and the inactive ingredients, hypromellose, silicon dioxide, sugar spheres, titanium dioxide Mar 29, 2024 · Zanaflex (tizanidine) is a short-acting muscle relaxer used to treat spasticity by temporarily relaxing muscle tone. Mar 27, 2024 · Tablets - Tizanidine Tablets USP, 4 mg are white to off white, oval, flat, beveled edged tablets debossed with “R180” on one side and “quadrisecting score” on other side. Emmanuel M. 5 mg/kg/day in 3 to 4 divided doses; maximum daily dose: 24 mg/ day. For multiple sclerosis or cerebral palsy, tizanidine tends to have fewer side effects than Baclofen. Find 341 user ratings and reviews for Tizanidine Oral on WebMD including side effects and drug interactions, medication effectiveness, ease of use and satisfaction Find 341 user ratings and reviews for Tizanidine Oral on WebMD including side effects and drug interactions, medication effectiveness, ease of use and satisfaction Find 346 user ratings and reviews for Tizanidine Oral on WebMD including side effects and drug interactions, medication effectiveness, ease of use and satisfaction Jul 6, 2022 · Zanaflex Capsules® are supplied as 2, 4, and 6 mg capsules for oral administration. Ther­ apy with conventional tizanidine I tried flexeril a long time ago. 48% of reviewers reported a positive experience, while 30% reported a negative experience. It can slow your reactions, so please take care if you are using tools or machines, or if you drive. Particularly liver damage. Tizanidine, sold under the brand name Zanaflex among others, is an alpha-2 (α 2) adrenergic receptor agonist, [2] similar to clonidine, that is used to treat muscle spasticity due to spinal cord injury, multiple sclerosis, and spastic cerebral palsy. Zanaflex made my life worth living again, after nearly 30 Years of pain. But others may only require closer monitoring. Consumer ratings and reviews for TIZANIDINE HYDROCHLORIDE (TIZANIDINE HYDROCHLORIDE). 60% of reviewers reported a positive effect, while 29% reported a negative effect. Nov 24, 2023 · Thank goodness my doctor put me on it for without this great medicine I would have no life at all. 5 hours and a peak plasma concentration (tmax) at 1. The mechanism by which tizanidine causes skeletal muscle relaxation is not well known; it appears to act at the level of spinal cord pain reflexes, most likely through activity as a Aug 15, 2023 · Potential decreased plasma clearance of tizanidine (by ≤50%) Avoid concurrent use, if possible. The recommended starting dose of tizanidine is 2 mg. Tizanidine acts on the central nervous system to help people relax. It's Reviews (347) Uses. 1, 7. Exclusion Tizanidine tablets, USP contain the active ingredient, tizanidine hydrochloride (2. This review of the long-term management of spasticity addresses some of the clinical dilemmas in the management of patients with chronic disability. Tizanidine metabolites have a t ½ of 20 to 40 hours and Nov 25, 2012 · Synopsis The central α2 adrenoceptor agonist tizanidine is a myotonolytic agent used in the treatment of spasticity in patients with cerebral or spinal injury. The pharmacokinetic and clinical properties of a modified release for­ mulation of the <Xz-adrenergic agonist tizanidine are reviewed. It was initially developed as a muscle relaxer and anti-spasmodic medication, but its anticonvulsive properties were discovered later. 0. lightheadedness, dizziness, or fainting. 4 Some studies have shown that tizanidine reduces spasticity from baseline on the Ashworth score compared to a placebo group and demonstrates a reduction in the frequency of daytime spasms. Tizanidine. Tizanidine is metabolized (broken down) in the liver. 7. Recommended starting dose: 2 mg; dose can be repeated at 6 to 8 hour intervals, up to a maximum of 3 doses in 24 hours (2. 2)]. Over the disease course other findings can include eye movement abnormalities (nystagmus, abnormal pursuit and Tizanidine is an antispastic agent with similar efficacy to that of baclofen and a more favourable tolerability profile and, while drowsiness is a frequently reported adverse effect with both agents, subjective muscle weakness appears to be less of a problem with tIZanidine than with bacl ofen. 50 (95% CI, 1. Tizanidine Tablets, USP is contraindicated in patientstaking potent inhibitors of CYP1A2, such as fluvoxamine or Aug 15, 2022 · Tizanidine is a medication that can help treat spinal and nervous system conditions. Apr 4, 2021 · The American College of Physicians also does not recommend trazodone in its 2021 insomnia treatment guidelines. Two fair-quality meta-analyses (not systematic reviews) evaluated unpublished trials on tizanidine versus baclofen or diazepam. The most common adverse effects associated with tizanidine are dry mouth and somnolence/drowsiness. Do not take more than 36 mg within a 24-hour period. Â Dosage. This medication has a short half-life and it gets completely tizanidine may be effective [11], insufficient data exist regarding its impact on motor function improvement and its side-effect profile. Zanaflex Capsules® contain the active ingredient, tizanidine hydrochloride (2. F. Ratings & Reviews. Review articles on tizanidine report cases of severe hepatotoxicity, acute liver failure, and death. Mean muscle tone scores (as measured by the Ashworth Scale) More about Tizanidine. It is commonly prescribed for the following purposes: Muscle spasms: Flexeril is often prescribed to treat muscle spasms associated with injuries‚ sprains‚ strains‚ or other musculoskeletal trauma. 5 hours, while Flexeril’s half-life is 18 hours. Call your doctor for medical advice about side effects. This medicine has made me hallucinate, faint, have irregular heart rate, have muscle twitching in my legs, but it is the only medication that helps me sleep. Children—Use and dose must be determined by your doctor. Generally, you shouldn’t take more than 3 doses per day. Note: In adults, when discontinuation of therapy is necessary, doses are gradually tapered by 2 to 4 mg daily. For some reason, only my noon pills make me "loopy. User Reviews & Ratings. 6 However, these agents were associated with a 50% increased risk of adverse events (AEs) with a relative risk of 1. 8. Design Systematic review and meta-analysis of randomised controlled trials. This medication is used to treat muscle spasms caused by certain conditions (such as multiple sclerosis, spinal cord injury). Feeling tired or weak. gov, clinicialtrialsregister. 14–1. Adagrasib. Tizanidine and Flexeril (cyclobenzaprine) have their differences. I was cautious and took half tablet after dinner. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. Spasm frequency and clonus are also reduced by tizanidine. Tizanidine: A Review Clinical Efficacy Tolerability Dosage and Administration 437 The antispastic efficacy of tizanidine has been demonstrated in several placebo­ controlledtrials, with wide interpatientvariation in effective and tolerated dosage (2 to 36 mg/day). OBJECTIVE . If concomitant use is necessary, reduce initial tizanidine dosage and rate of subsequent dosage titration. slow or irregular heartbeat. com Jul 22, 2021 · Medically reviewed by Femi Aremu, PharmD — Written by University of Illinois — Updated on July 22, 2021. 6 This action decreases the release of excitatory amino acids from spinal interneurons. We surveyed the published literature for data on potential tizanidine dose relationships to pharmacokinetics, drug safety and effectiveness, as well as to provide practical Aug 28, 2023 · Tizanidine use requires caution in patients with hepatic impairment. I was just reading up on Tizanidine and I'm a bit concerned regarding the side effects. ³. 2 mg every six to eight hours The dose may increase by 2 to 4 mg every one to four days until effective; The dose should not exceed 36 mg in one day Feb 13, 2018 · The effects of withdrawal are similar to those of tizanidine withdrawal, but with a major impact on the vascular balance: hypertensive outbreak, severe tachycardia, tachypnea, and hypothermia sensation. Got very drowzy and napped. The dose of tizanidine can be gradually increased by 2–4 mg per dose, with intervals of 1–4 days between each increase, until a satisfactory reduction in muscle tone is achieved. If you have questions about side effects, call your doctor. Ordinarily avoid concomitant use; if concomitant use is necessary, use with Oct 9, 2020 · Tizanidine Tablets, USP 2 mg are white to off-white, round, flat beveled, uncoated tablets debossed with product code “502” on one side, and bisecting score on the other. Taking it as directed can decrease the risk of adverse effects and improve treatment outcomes. unusual tiredness or weakness. The aim of this study was to compare the efficacy of tizanidine with placebo in terms of postoperative pain scores, analgesic consumption, return to daily activity and health-related quality of life. 1 out of 10 from a total of 374 ratings on Drugs. Feb 25, 2020 · Dry mouth. Therapy with conventional tizanidine tablets is effective in the relief of spasticity, but it has a short half-life, resulting in it having to be administered three or four times daily. Jul 8, 2021 · Objective To investigate the efficacy, acceptability, and safety of muscle relaxants for low back pain. Summary data are provided in Table 2. See full list on drugs. Overall rating 5. This medication is a muscle relaxant. Alyssa Billingsley, PharmD Alyssa Billingsley, PharmD, is a For oral dosage forms (capsules or tablets): For muscle relaxation: Adults—At first, 2 milligrams (mg) every 6 to 8 hours. Tizanidine oral tablet is a prescription drug that's used to manage muscle spasms. Nov 27, 2001 · SCA8 is a slowly progressive ataxia with onset typically in the third to fifth decade but with a range from before age one year to after age 60 years. Unfortunately it was not effective for me. Pain from fibromyalgia can have a severe impact on your quality of life, making even normal tasks difficult. 6 / 10. Abstract. 4 years. loss of consciousness. Overdosing on tizanidine can cause liver damage and other harmful side effects. Eligibility criteria for study selection Randomised controlled trials Find 347 user ratings and reviews for Tizanidine Oral on WebMD including side effects and drug interactions, medication effectiveness, ease of use and satisfaction Aug 1, 2004 · Although this systematic review found some evidence of increased effectiveness of tizanidine compared to baclofen and diazepam, it is not possible to determine whether these conclusions are valid. Jul 18, 2020 · Hi youtubers! I had a really good run with Zanaflex while it lasted but ever since my flare up in May I've been much more exhausted and experiencing brain fo Nov 2, 2020 · The sedative nature of this drug means taking tizanidine for anxiety might be an option. Clinical Pharmacology. 29 mg equivalent to 2 mg tizanidine base, 4. Apr 1, 2024 · Tizanidine is often taken on an as-needed basis. D [email protected] Department of Pharmaceutical Services, University of California Los Angeles, Santa Monica Medical Center, Santa Monica, California, USA Apr 13, 2012 · Tizanidine User Reviews & Ratings (Page 5) Brand names: Zanaflex. pv jg sk rp fz jd pz jf lb mq